Fascicle

For in vivo research

Notes at the bench.
Analysis at the desk.

Fascicle is the research record designed around how wet-lab work actually happens. Capture observations offline on mobile. Review, audit, and analyze on desktop. Welfare alerts and one-click exports built in.

Invitation-only during beta.
fascicle.app / experiments / EX-27 / explore
Experiments·EX-27 Chronic stress, DBA/2J

Explore

›Show body-weight trajectories per treatment group over the first 14 days, with SEM.
reads cataloganimal_trendgroup_comparedone · 8.2s
949698100102% baselined1d4d7d10d14
Vehicle (n = 8)Compound A, 10 mg/kg (n = 8)Compound A, 30 mg/kg (n = 8)
Answer

All three arms track within 1% of baseline through day 3. From day 5, 30 mg/kg shows a ~6% mean drop sustained through day 14 (p < 0.05 vs vehicle, two-way ANOVA). 10 mg/kg and vehicle remain within 2% of baseline and are not statistically distinguishable in this window.

8:14
offline
Today · Apr 22

3 sessions queued

Kessler Lab · EX-27 chronic stress

In progress · body weight
12 / 20
8 queued · will sync when online
Clinical score — cohort B
n = 16
09:30
Drug dosing — 30 mg/kg arm
n = 8 · compound A
11:00
Today
Session
Animals
Sync

At the bench

Capture what happened — even without signal.

Pull today's tasks before rounds. Record body weights, clinical scores, dosing, and voice notes straight from your phone — WatermelonDB stores everything locally so airplane wifi, basements, and vivarium dead zones don't lose a single observation.

  • Offline-first on iOS and Android
  • Scan a QR cage card → jump to that animal's form
  • Hold to record voice; Whisper transcribes into the log
  • Auto-sync when you reconnect — conflicts resolved append-only

At the desk

The welfare alerts you wish you had.

Body-weight drop, clinical-score rubric, tumor-volume thresholds, and post-op schedules surface before a protocol goes off-rails — configurable per experiment, escalated up the chain only if the PI hasn't already acknowledged.

  • Per-experiment thresholds (strain- and arm-aware)
  • Trend alerts, not just snapshots — “three days of loss” matters
  • Grace ladder: device → PI → lab admin
  • Audit trail on every acknowledgement — useful for IACUC audits
RAT-037·Cohort B · 30 mg/kg

Weight −11% over 3 days

RAT-041·Cohort B · 30 mg/kg

Clinical score 3 — piloerection + hunched

RAT-019·Cohort A · vehicle

Post-op day 3 schedule generated

Everything else

Built around the whole lifecycle

AI analyst (Explore)

Ask in plain English — Fascicle runs the query, charts the result, and shows the exact filter chain it used so you can verify every number.

Bring your data in

Paste CSV into the import wizard, or drop EthoVision, ANY-maze, Noldus, or Bonsai exports. Column mappings save per template.

Templates, not schemas

Body weight, open field, dosing, welfare — nine field types cover the long tail. Clone a template, adjust for your assay, done.

Print-ready QR cage cards

Cage cards, animal IDs, and session sheets generate as print-ready PDFs. Scan at the bench to jump to that animal.

Per-animal timeline

Every observation, dose, welfare event for one rat on a single printable page. Exactly what a necropsy or a paper appendix wants.

Exports that fit your workflow

Prism-ready CSVs with group + SEM prebaked. R-friendly long-format. Excel-friendly wide. No copy-paste gymnastics.

Working principles

Designed alongside researchers, not around them

Append-only

Observations are immutable once committed. Retractions are first-class, audited, and reversible — no silent edits.

No productivity scoring

We don't track who logged how many observations. Ever. Science isn't a leaderboard.

Your data, exportable

Every observation, trial, and session exports cleanly to Prism, R, Excel, and CSV. Leave any time with everything intact.